The global endoscopic submucosal dissection (ESD) market was valued at USD 370.4 million in 2024 and is projected to expand to USD 512.0 million by 2030, growing at a compound annual growth rate (CAGR) of 5.5% from 2025 to 2030. This growth is primarily driven by the increasing prevalence of gastrointestinal cancers and other related disorders, combined with continuous advancements in endoscopic technology and instrumentation. These developments have significantly improved the efficiency, safety, and accessibility of minimally invasive diagnostic and therapeutic procedures, such as ESD.

One of the major growth catalysts for this market is the rising incidence of gastrointestinal cancers worldwide. For example, according to estimates from the American Cancer Society, 26,890 new cases of stomach cancer are expected in 2024 in the United States alone, comprising 10,730 cases among women and 16,160 cases among men. As the rates of esophageal, gastric, and colorectal cancers continue to increase globally, the demand for advanced and precise treatment options like ESD is expected to grow substantially.

Another key factor contributing to market growth is the rapidly aging global population, which is more susceptible to gastrointestinal conditions, including cancers. Gastric cancer predominantly affects older individuals, with the average age of diagnosis being 68 years, and 6 out of 10 cases annually occurring in people aged 65 or older. Furthermore, older patients often suffer from multiple health conditions, making traditional open or laparoscopic surgeries riskier. In such scenarios, ESD offers a less invasive alternative with reduced recovery times, thereby making it an increasingly preferred option in geriatric care.

Key Market Trends & Insights:

• North America led the global ESD market in 2024, accounting for 40.1% of total revenue. This dominance is attributed to well-developed healthcare infrastructure, higher adoption rates of advanced medical technologies, and robust reimbursement frameworks.
• The Asia Pacific region is expected to witness the fastest growth during the forecast period, driven by a large patient base, growing awareness of minimally invasive procedures, and increased investment in healthcare infrastructure, particularly in countries such as Japan, China, and South Korea.
• The knives segment accounted for the largest share of 32.0% in 2024 and is projected to grow at the fastest CAGR over the forecast period. This is due to their essential role in performing precise dissections during ESD procedures. The gastroscopes and colonoscopes segment is also anticipated to grow at a significant pace, supported by their widespread use in diagnosing and treating upper and lower gastrointestinal tract disorders.
• The stomach cancer segment held the largest market share at 48.2% in 2024, underscoring the high prevalence of gastric cancer cases globally. The colon cancer segment is projected to grow at the fastest CAGR during the forecast period, fueled by increasing screening programs and early detection initiatives.
• Hospitals dominated the market with a 56.3% share in 2024 and are expected to maintain their lead while also growing at the fastest CAGR. Their dominance is due to the availability of advanced endoscopic equipment, trained specialists, and comprehensive patient care facilities. Outpatient facilities are expected to record the fastest growth rate over the forecast period, owing to the growing preference for same-day procedures, cost-effectiveness, and shorter waiting times compared to hospital settings.

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Market Size & Forecast:

• 2024 Market Size: USD 370.4 Million
• 2030 Projected Market Size: USD 512.0 Million
• CAGR (2025-2030): 5.5%
• North America: Largest market in 2024

Key Players

The following are the leading companies in the endoscopic submucosal dissection market. These companies collectively hold the largest market share and dictate industry trends.

• Olympus Corporation
• Boston Scientific Corporation
• PENTAX Medical (Hoya Corporation)
• FUJIFILM Holdings Corporation
• Karl Storz GmbH & Co. KG
• Micro-Tech Endoscopy
• Medtronic
• CONMED Corporation
• STERIS plc.
• Cook Group
• Creo Medical

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Conclusion:

The global endoscopic submucosal dissection market is on a steady growth trajectory, fueled by the rising prevalence of gastrointestinal cancers, an expanding elderly population, and ongoing technological advancements in endoscopic tools and techniques. With its ability to provide a minimally invasive, precise, and effective alternative to traditional surgery particularly for high-risk and elderly patients ESD is gaining significant traction worldwide. While North America currently leads the market in terms of revenue, the Asia Pacific region is poised for the fastest growth, supported by a large patient base and increasing adoption of advanced medical procedures. Product innovation, coupled with the expanding use of ESD in diverse cancer treatments, will continue to shape the market landscape, positioning it as a critical component in the global fight against gastrointestinal diseases.